![]() ![]() It is predicted that losartan minimum effective plasma concentration can be achieved in transdermal administration through this transport improvement in normal application area. However, such pretreatment enhanced losartan permeation rate and efficiency 21 and 23-fold higher respectively for 10 mg/mL the potassium losartan concentration. It is showed that oleic acid pretreatment did not effect on losartan permeation rate and efficiency of 2 mg/mL potassium losartan concentration. The transport profiles were analyzed based on the lag time diffusion method. Atlet bisa menentukan sendiri tempo larinya, cepat, lambat atau pun jalan. Fartlek atau speedplay adalah latihan yang berupa lari di alam terbuka untuk selama 1 sampai 3 jam. Losartan transport from such solutions with and without oleic acid one hour pretreatment were tested using male Wistar rat skin as a membrane for 30 hours in vertical diffusion sel. Fartlek adalah sistem latihan yang sangat baik untuk semua cabang olahraga, terutama untuk cabang olahraga yang memerlukan daya tahan. 2 mg/mL and 10 mg/mL using propylene glycol 15% as solubilizing agent. Potassium losartan solutions in citric buffer pH 5.0 were made in two levels of concentration i.e. The effect of oleic acid on losartan transdermal permeation has been observed to explore its ability as chemical enhancer. ![]()
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